IMPACT OF WADDLIA CHONDROPHILA INFECTION ON PREGNANCY IN THE MOUSE

Impact of Waddlia chondrophila infection on pregnancy in the mouse

The intracellular bacterium Waddlia chondrophila, which belongs to the Chlamydiales order, was found to be associated with miscarriage in humans.There is little to no knowledge regarding the mode of infection, impact on the neonate and pathophysiology of this emerging bacterium.We have previously shown that W.chondrophila induces a systemic infecti

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The impacts associated with having ADHD: an umbrella review

IntroductionAttention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention.These symptoms are significantly impairing and carry additional risks for children and adults with ADHD, including negative mental health (e.g.depression), physical health (e.g

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Role of critical elements in botulinum neurotoxin complex in toxin routing across intestinal and bronchial barriers.

The highly potent botulinum neurotoxin serotype A (BoNT/A) inhibits neurotransmitter release at neuromuscular junctions resulting in flaccid muscle paralysis, respiratory arrest and death.In order to reach their Granola neuronal cell targets, BoNT/A must cross epithelial cell barriers lining the intestines and airways.The toxin is produced as a lar

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